以下信息为主动公开的研究生招生宣传信息
目录
王晓帆   更新日期: 2025年12月13日
王晓帆,女,汉族,1989年3月生,吉林人,群众,博士研究生学历,教授,博、硕导。
邮箱地址  xxw033@scau.edu.cn
个人简介
华南农业大学动物科学学院教授、博士生导师,于2023年入选国家高层次青年人才项目。长期从事猪肠道微生物与宿主营养代谢互作研究,聚焦肉品质提升和非粮饲料资源开发的关键策略与机制解析。在猪肠道菌群动态演变规律、微生物培养组学等方向取得重要突破,相关成果发表于《Microbiome》、《mSystems》、《Journal of Animal Science and Biotechnology》等国际权威期刊;美国授权专利1项,申请国内专利3项。主持国家自然科学基金2项、作为骨干主持或参与国家“十四五”重点研发计划子课题2项、国家自然科学基金创新群体项目(B类)等。
工作经历
2023/12- 至 今     华南农业大学动物科学学院,教授
2022/10-2023/11 华南农业大学动物科学学院,副教授
2019/08-2022/08 美国阿肯色大学,博士后
教育经历
2015/01-2019/07 美国阿肯色大学,动物科学专业,博士                                                    
2012/08-2014/12 美国阿肯色大学,动物科学专业,硕士                                                  
2008/09-2012/07 吉林农业大学,动物医学专业,本科
社会、学会及学术兼职
广东省畜牧兽医学会饲料营养分会理事,Animal Nutriomics和《农业生物技术学报》青年编委,Microorganisms和Life期刊的客座编辑。
研究领域
1.挖掘猪肠道纤维素降解菌提升饲料利用效率                                                                                                                                                      
2.肠道菌群次级代谢产物提升猪肉品质                                                                                                                                            
3.猪肠道微生物培养组学及益生微生态制剂研发
科研项目
2026-2030           国家自然科学基金创新群体项目(B类),1200万,骨干。
2024.01-2026.12  国家自然科学基金委高层次青年人才项目-猪肠道微生物组影响饲料转化率的机制(23DAA00403),200万,主持。
2023.12-2028.12  十四五国家重点研发计划子课题-骨骼肌纤维类型影响肌内脂肪含量的研究及营养调控(2023YFD1301300),30万,骨干。
2023.01-2025.12  国家自然科学基金(青年项目)-成年猪异源肠道微生物介导仔猪初级胆汁酸合成的机制研究(32202715),30万,主持。
2023-2025            特定高校学科建设项-国猪免疫特征的肠道微生物机制(2023B10564001),50万,骨干。
2022.12-2027.11 十四五重点研发计划子课题-肠道菌群成熟度影响动物消化发育的机制(2022YFD1300402),30万,骨干。
2023.12-2026.11 十四五重点研发计划中美国际合作项目-早期断奶应激影响仔猪肠道干细胞和菌群发育及其互作的分子机制(2023YFE0124400),150万,参与。
发表论文
1) Liu X., Quan J., Li Y., Wang X.F., and Zhao J., 2025. Advancing cellulose degradation through synthetic biology: engineered pathways and microbial systems for sustainable biomass conversion. Journal of Animal Science and Biotechnology, accepted.
2) Dou, C., Qu, H., Qin, Y., Wang, X.F., Yan, H., Li, R., Zhao, Y., Zhou, J., and Wang, X., 2025. TSC2/mTORC1 integrates deoxynivalenol signals recognized by membrane receptors IR and EGFR to restrict intestinal stem cell function. Journal of Hazardous Materials, 494:138769
3) Song, X., Jin, C., Wu, R., Wang, Y., and Wang, X.F., 2025. Gut microbiota and metabolites in lipid metabolism and intramuscular fat deposition: mechanisms and implications for meat quality. Journal of Animal Science and Biotechnology, 16(1), 147.
4) Dou, C., Qu, H., Qin, Y., Wang, X.F., Zhou, J., Wang, X., and Yan, H., 2025. L-Glutamate enables the EGFR-MEK-ERK-mTFB2 axis to enhance mitochondrial biogenesis in intestinal stem cells. Stem Cell Research & Therapy, 16(1):599.
5) Hu, T., Dou, C., Huang, Q., Wang, X.F., Yan, H., Zhou, J., Li, R., Zhao, Y., and Wang, X., 2025. IP3R-dependent Ca2+ signaling in the endoplasmic reticulum is required for deoxynivalenol-induced intestinal stem cell injury. Biochemical Pharmacology, 242(Pt 3):117228.
6) Zan, G., Qu, H., Meng, J., Wang, X.F., Yan, H., Wang, X., and Zhou, J., 2025. Matrine disturbs the eimeria necatrix-induced loop of tuft cell-intestinal stem cell-goblet cell by inactivating IL-13/JAK2/STAT3 signaling. Poultry Science, 104(2):104786.
7) Cui, J., Tang, L., Li, Z., Wang, S., Zhou, J., Yan, H., and Wang, X.F., 2025. Active Factors in the Adult Pig Colon: Microbial Transplantation Versus Supplementation with Metabolites in Weaned Piglets. Microorganisms, 13(11), 2533.
8) Zan, G., Wang, X.F., Yan, S., Qin, Y., Yao, L., Gao, C., Yan, H., Zhou, J., and Wang, X., 2024. Matrine reduced intestinal stem cell damage in eimeria necatrix-infected chicks via blocking hyperactivation of Wnt signaling. Phytomedicine, 128:155363.
9) Wang,*X.F., Tsai,*T.C., Deng,F., Wei,X., Chai,J., Knapp,J., Apple,J., Maxwell,C.V., Lee,J.A., Li,Y and J.Zhao., 2019. Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria. Microbiome, 7(1),p.109 (“高被引”).
10) Wang,* X.F., Tsai,*T., Zuo,B., Wei,X., Deng,F., Li,Y., Maxwell,C.V., Yang,H., Xiao,Y.P., and Zhao,J., 2022. Donor growth stage and phenotype determine the effects of FMT on growth performance, gut microbiota development, and metabolic potentials in recipient pigs. Journal of Animal Science and Biotechnology, 13(5),1483-1498.
11) Wang,X.F., Howe,S., Wei,X., Deng,F., Tsai,T., Chai,J., Xiao,Y., Yang,H., Maxwell,C.V., Li,Y. and Zhao,J., 2021.Comprehensive cultivation of the swine gut microbiome reveals high bacterial diversity and guides bacterial isolation in pigs. mSystems,6(4),pp.e00477-21.
12) Wang,X.F., Tsai,T., Wei,X., Zuo,B., Davis,E., Rehberger,T., Hernandez,S., Jochems,E.J., Maxwell,C.V. and Zhao,J., 2021. Effect of Lactylate and Bacillus subtilis on growth performance, peripheral blood cell profile, and gut microbiota of nursery pigs. Microorganisms, 9(4),p.803.
13) Wang,X.F., Howe,S., Deng,F. and Zhao,J., 2021. Current applications of absolute bacterial quantification in microbiome studies and decision-making regarding different biological questions. Microorganisms,9(9),p.1797.
14) Zhu,C., Liang,S., Zan,G., Wang,X.F., Gao,C., Yan,H., Wang,X., and Zhou,J., et al., 2022. Selenomethionine alleviates DON-Induced oxidative stress via modulating Keap1/Nrf2 Signaling in the Small Intestinal Epithelium, Journal of Agricultural and Food Chemistry, 71:895-904.
15) Chen,J., Li,Z., Wang,X.F., Fan,B., Deng,F., D. Yu,H., Ze, X., Zhu, L., Yin,Y., Chen,Y., Zhao,J.,Y ang,Y., and Wang,X., 2022. Isomaltooligosaccharides Sustain the Growth of Prevotella Both In Vitro and in Animal Models. Microbiology Spectrum, 10(6),e02621-21.
16) Li,Y., Wang,X.F., Wang,X.Q., Wang,J. and Zhao,J., 2020. Life-long dynamics of the swine gut microbiome and their implications in probiotics development and food safety. Gut Microbes, pp.1-9.
17) Yang,Q., Liu,J., Wang,X.F., Robinson,K., Whitmore,M.A., Stewart,S.N., Zhao,J., and G. Zhang., 2021. Identification of an intestinal microbiota signature associated with the severity of necrotic enteritis.Frontiers in Microbiology, 12.
18) Deng,F., McClure,M., Rorie,R., Wang,X.F., Chai,J., Wei,X., Lai,S. and Zhao,J., 2019. The vaginal and fecal microbiomes are related to pregnancy status in beef heifers. Journal of Animal Science and Biotechnology, 10(1),pp.1-13.
19) Deng,F., Peng,Y., Zhang,Z., Howe,S., Wu,Z., Dou,J., Li,Y., Wang,X.F., LiangY., Zhao,J., and Li,Y. 2022. Weaning time affects the archaeal community structure and functional potential in pigs. Frontiers in Microbiology, 918.
20) Deng,F., Li,Y., Peng,Y., Wei,X., Wang,X.F., Howe,S., Yang,H., Xiao,Y., Li,H., Zhao,J., and Li,Y.,2021. The diversity, composition, and metabolic pathways of archaea in pigs. Animals, 11(7),p.2139.
21) Tsai,T., Sales,M.A., Kim,H., Erf,G.F., Vo,N., Carbonaro,F., VanDerMerwe,M., Kegley,E.B., Buddington,R., Wang,X.F. and Maxwell,C.V., J.Zhao, 2018. Isolated rearing at lactation increases gut microbial diversity and post-weaning performance in pigs. Frontiers in Microbiology, 9.
22) Wang,Q., Chen,X., Hu,H., Wei,X., Wang,X.F., Peng,Z., Ma,R., Zhao,Q., Zhao,J., Liu,J. and Deng,F., 2021. Structural changes in the oral microbiome of the adolescent patients with moderate or severe dental fluorosis. Scientific Reports, 11(1),pp.1-9.
23) Beane,*K.E., Redding,*M.C., Wang,*X.F., Pan,J.H., Le,B., Cicalo,C., Jeon,S., Kim,Y.J., Lee,J.H., Shin,E.C. and Li,Y., 2021. Effects of dietary fibers, micronutrients, and phytonutrients on gut microbiome: a review. Applied Biological Chemistry, 64(1),1-18.
专著教材
Wang,X., and Zhao J (2019). Advances in sequence technologies for generating poultry gut microbiome data. Invited book chapter for Improving gut function poultry, Editor: StevenRicke
科研创新
授权发明专利:
(1)ZHAO Jiangchao, WANG Xiaofan, TSAI Tsungcheng, MAXWELL Charles V. Swine origin probiotics that promote health and growth performance in pigs. Patent No.: US 12,220,435 B2.
申请发明专利:
(1)王晓帆,王双,李子轩,唐烈发,王修启,赵江潮. 瘤胃球菌及其体外纯培养代谢上清液在促进仔猪肠道发育中的应用. 申请号:CN202510983175.7
(2)王晓帆,崔建昊,赵江潮,王修启,周加义. 埃氏巨球形菌在促进仔猪肠道发育中的应用. 申请号:CN202510918587.2
(3)王晓帆,宋晓凤,赵江潮,王修启,金成龙. α-酮丁酸在促进骨骼肌纤维类型从快肌转化为慢肌中的应用. 申请号:CN202511571256.2
教学活动
担任2024级丁颖创新班第二班主任                                                                                                                                    
本科课程:《饲料卫生学》
指导学生
在读博士3名,硕士6名
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