目录
研究方向:动物源细菌耐药性有关研究,包括动物源细菌耐药性监测、细菌耐药及进化机制、耐药性逆转等
华南农业大学青年骨干教师
广州市珠江科技新星
教育部青年长江学者
广东省青年珠江学者
广东省兽药研制与安全评价重点实验室副主任
华南农业大学兽医学院兽医药理学与毒理学教研室主任
2015-10 至 2016-04,华南农业大学,兽医学院,副教授
2013-10 至 2015-09,华南农业大学,兽医学院,讲师
2007-2012年,华南农业大学,兽医学院,研究生/博士,刘雅红教授
2017 广东省“青年珠江学者”
2018 教育部“长江学者奖励计划”青年学者
2020 教育部“霍英东教育基金会第十七届高等院校青年教师奖”
2021 广东省“南粤优秀教师”
2022 广东省科学技术奖自然科学奖一等奖
antibiotics编委
《中国兽医杂志》编委
《养禽与禽病防治》编委
《基因组学与应用生物学》编委
《华南农业大学学报》青年编辑委员会委员
中国食品法典抗微生物耐药性专业委员会委员
国家自然科学基金委创新研究群体核心成员
农业农村部兽药评审咨询专家库专家
中国畜牧兽医学会 兽医药理毒理学分会副理事长
(2) 国家自然科学基金委员会,创新研究群体项目,32121004,畜禽病原菌耐药及防控机制研究,2022-01-01至2026-12-31,1000万元,在研,参与;
(3) 国家自然科学基金委员会,面上项目,31972735,去甲肾上腺素激活SOS信号通路促进多重耐药质粒转移的机制研究,2020-01-01至2023-12-31,59万元,资助期满,主持;
(4) 国家自然科学基金委员会,国际(地区)合作与交流项目,31981330049,理解食物链中抗生素耐药性传播驱动因素,2019-01-01至2019-12-31,14.9万元,结题,参与;
(5) 广东省科学技术厅,广东省基础与应用基础研究重大项目子课题,2020B0301030007,畜禽病原高致病力的分子机制和防控基础研究,2022-06至2026-06,200万元,在研,主持;
(6) 中华人民共和国科学技术部,国家重点研发计划课题,2022YFD1800404,畜禽重要耐药病原菌的定植与持留规律,2022-11至2025-12,380万元,在研,主持;
(7) 岭南现代农业科学与技术广东省实验室,双聘团队重大科技研究专项,NT2021006,畜禽病原菌耐药及防控机制研究,2021-10至2024-09,1500万元,在研,参与;
(8) 国家自然科学基金委员会,重点国际(地区)合作研究项目,U0631006,质粒协助沙门菌的适应性及其机制研究,2016-01至2020-12,349.98万元,结题,参与;
(9) 中华人民共和国科学技术部,国家重点研发计划,2017YFD0501404,畜禽重要原料和制剂生产工艺改进与产品质量提升,2017-07至2020-12,98.3万元,结题,参与;
(10) 中华人民共和国科学技术部,国家重点研发计划子课题,2016YFD0501301,畜禽病原菌耐药性检测技术研究,2016-07至2020-12,66万元,结题,主持。
(2) Jian Sun; Xiao-Ping Liao; Alaric W.D’Souza; Manish Boolchandani; Sheng-Hui Li; Ke Cheng; José Luis Martínez; Liang Li; You-Jun Feng; Liang-Xing Fang; Ting Huang; Jing Xia; Yang Yu; Yu-Feng Zhou; Yong-Xue Sun; Xian-Bo Deng; Zhen-Ling Zeng; Hong-Xia Jiang; Bing-Hu Fang; You-Zhi Tang; Xin-Lei Lian; Rong-Min Zhang; Zhi-Wei Fang; Qiu-Long Yan; Gautam Dantas; Ya-Hong Liu ; Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms, Nature Communications, 2020, 11(1): 1427.(共同第一作者)
(3) Hao Ren; Zixing Zhong; Shuang Zhou; Yiyang Wei; Yujiao Liang; Huiling He; Zijian Zheng; Mengyuan Li; Qian He; Tengfei Long; Xinlei Lian; Xiaoping Liao; Yahong Liu; Jian Sun ; CpxA/R Controlled Nitroreductase Expression as Target for Combinatorial Therapy against Uropathogens by Promoting Reactive Oxygen Species Generation, Advanced Science, 2023, 10(25).(唯一通讯作者)
(4) Zi-xing Zhong; Shuang Zhou; Yu-jiao Liang; Yi-yang Wei; Yan Li; Teng-fei Long; Qian He; Meng-yuan Li; Yu-feng Zhou; Yang Yu; Liang-xing Fang; Xiao-ping Liao; Barry N. Kreiswirth; Liang Chen; Hao Ren; Ya-hong Liu; Jian Sun ; Natural flavonoids disrupt bacterial iron homeostasis to potentiate colistin efficacy, Science Advances, 2023, 9(23): 4205.(共同通讯作者)
(5) Hao Ren; Yuan-Wei Pan; Jia-Hao Zhong; Jia-Yi Wang; Zhao-Xiang Lu; Qian He; Shi-Ying Zhou; Xiao-Ping Liao; Ya-Hong Liu; Tai-Cheng An; Jian Sun ; An antibiotic-destructase-activated Fentonlike catalyst for synergistic removal of tetracycline residues from aquatic environment, Chemical Engineering Journal, 2023, 459: 141576.(共同通讯作者)
(6) Chong Chen; Chao-Yue Cui; Yan Zhang; Qian He; Xiao-Ting Wu; Gong Li; Xiao-Ping Liao; Kreiswirth, Barry N.; Ya-Hong Liu; Liang Chen; Jian Sun ; Emergence of mobile tigecycline resistance mechanism in Escherichia coli strains from migratory birds in China, Emerging Microbes & Infections, 2019, 8(1): 1219-1222.(共同通讯作者)
(7) Chong Chen; Chao-Yue Cui; Jun-Jun Yu; Qian He; Xiao-Ting Wu; Yu-Zhang He; Ze-Hua Cui; Cang Li; Qiu-Lin Jia; Xiang-Guang Shen; Ruan-Yang Sun; Xi-Ran Wang; Min-Ge Wang; Tian Tang; Yan Zhang; Xiao-Ping Liao; Kreiswirth, Barry N.; Shi-Dan Zhou; Bin Huang; Hong Du; Jian Sun; Liang Chen; Ya-Hong Liu ; Genetic diversity and characteristics of high-level tigecycline resistance Tet(X) in Acinetobacter species, Genome Medicine, 2020, 12(1): 0-111.(共同通讯作者)
(8) Xi-Ran Wang; Xin-Lei Lian; Tian-Tian Su; Teng-Fei Long; Meng-Yuan Li; Xiao-Yin Feng; Ruan-Yang Sun; Ze-Hua Cui; Tian Tang; Jing Xia; Ting Huang; Ya-Hong Liu; Xiao-Ping Liao; Liang-Xing Fang; Jian Sun ; Duck wastes as a potential reservoir of novel antibiotic resistance genes, Science of the Total Environment, 2021, 771: 0-144828.(唯一通讯作者)
(9) Yu-Zhang He; Xu Kuang; Teng-Fei Long; Li Gong; Hao Ren; Bing He; Jin-Ru Yan; Xiao-Ping Liao; Ya-Hong Liu; Liang Chen; Jian Sun ; Re-engineering a mobile-CRISPR/Cas9 system for antimicrobial resistance gene curing and immunization in Escherichia coli, Journal of Antimicrobial Chemotherapy, 2021, 77(1): 74-82.(唯一通讯作者)
(10) Yu-Zhang He; Jin-Ru Yan; Bing He; Hao Ren; Xu Kuang; Teng-Fei Long; Cai-Ping Chen; Xiao-Ping Liao; Ya-Hong Liu; Jian Sun ; A Transposon-Associated CRISPR/Cas9 System Specifically Eliminates both Chromosomal and Plasmid-Borne mcr-1 in Escherichia coli, Antimicrobial Agents and Chemotherapy, 2021, 65(10).(唯一通讯作者)
(11) Qian He; Chao-Yue Cui; Xiao-Jing Zhang; Zhuo-Yu Lin; Qiu-Lin Jia; Cang Li; Hao Ren; Da-Tong Cai; Zi-Jian Zheng; Teng-Fei Long; Xiao-Ping Liao; Ya-Hong Liu; Jian Sun ; Reducing tetracycline antibiotics residues in aqueous environments using Tet(X) degrading enzymes expressed in Pichia pastoris, Science of the Total Environment, 2021, 799(2021): 0-149360.(唯一通讯作者)
(12) Chao-Yue Cui; Qian He; Qiu-Lin Jia; Cang Li; Chong Chen; Xiao-Ting Wu; Xiao-Jing Zhang; Zhuo-Yu Lin; Zi-Jian Zheng; Xiao-Ping Liao; Barry N. Kreiswirth; Ya-Hong Liu; Liang Chen; Jian Sun ; Evolutionary Trajectory of the Tet(X) Family: Critical Residue Changes towards High-Level Tigecycline Resistance, mSystems, 2021, 6(3): e00050-21.(共同通讯作者)
(13) Lu Han; Xu-Wei Liu; Tao Zang; Hao Ren; Dun-Sheng Liang; Shuan-Cheng Bai; Cang Li; Xiao-Ping Liao; Ya-Hong Liu; Chaoqun Zhang; Jian Sun ; H2S responsive PEGylated poly (lipoic acid) with ciprofloxacin for targeted therapy of Salmonella, Journal of Controlled Release, 2022, 351: 896-906.(共同通讯作者)
(14) Lu Han; Tao Zang; Lulu Tan; Dunsheng Liang; Tengfei Long; Xuwei Liu; Xiaofan Shen; Hao Ren; ZhiPeng Li; Zhaoxiang Lu; Shengqiu Tang; Xiaoping Liao; Yahong Liu; Chaoqun Zhang; Jian Sun; Self-assembly of H2S-responsive nanoprodrugs based on natural rhein and geraniol for targeted therapy against Salmonella Typhimurium, Journal of Nanobiotechnology, 2023, 21(1).(共同通讯作者)
(15) Qian He; Zhuoyu Lin; Meilin Qin; Yu Huang; Zhaoxiang Lu; Mei Zheng; Chaoyue Cui; Cang Li; Xiaojing Zhang; Xiaoping Liao; Yahong Liu; Hao Ren; Jian Sun ; TET-Yeasate: An engineered yeast whole-cell lysate-based approach for high performance tetracycline degradation, Environment International, 2023, 179: 108158.(共同通讯作者)
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软件:
一种监测和分析细菌生长的软件,专利号:2016SR222188,排名第1