目录
2022/10-2023/11 华南农业大学动物科学学院，副教授
2019/08-2022/08 美国阿肯色大学，博士后
2012/08-2014/12 美国阿肯色大学，动物科学专业，硕士
2008/09-2012/07 吉林农业大学，动物医学专业，本科
2.肠道菌群次级代谢产物提升猪肉品质
3.猪肠道微生物培养组学及益生微生态制剂研发
2024.01-2026.12 国家自然科学基金委高层次青年人才项目-猪肠道微生物组影响饲料转化率的机制(23DAA00403)，200万，主持。
2023.12-2028.12 十四五国家重点研发计划子课题-骨骼肌纤维类型影响肌内脂肪含量的研究及营养调控(2023YFD1301300)，30万，骨干。
2023.01-2025.12 国家自然科学基金(青年项目)-成年猪异源肠道微生物介导仔猪初级胆汁酸合成的机制研究(32202715)，30万，主持。
2023-2025 特定高校学科建设项-国猪免疫特征的肠道微生物机制(2023B10564001)，50万，骨干。
2022.12-2027.11 十四五重点研发计划子课题-肠道菌群成熟度影响动物消化发育的机制（2022YFD1300402)，30万，骨干。
2023.12-2026.11 十四五重点研发计划中美国际合作项目-早期断奶应激影响仔猪肠道干细胞和菌群发育及其互作的分子机制（2023YFE0124400），150万，参与。
2.Liu, X., Quan, J., Li, Y., Wang, X.F.*, Zhao, J., 2026. Advancing cellulose degradation through synthetic biology: engineered pathways and microbial systems for sustainable biomass conversion. Journal of Animal Science and Biotechnology, 17(1): 12.
3.Song, X., Jin, C., Wu, R., Wang, Y., Wang, X.F.*, 2025. Gut microbiota and metabolites in lipid metabolism and intramuscular fat deposition: mechanisms and implications for meat quality. Journal of Animal Science and Biotechnology, 16(1): 147.
4.Wang, X.F., Tsai, T.C., Deng, F., Wei, X., Chai, J., Knapp, J., Apple, J., Maxwell, C.V., Lee, J.A., Li, Y., Zhao, J., 2019. Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria. Microbiome, 7(1): 109.（高被引）
5.Wang, X.F., Tsai, T., Zuo, B., Wei, X., Deng, F., Li, Y., Maxwell, C.V., Yang, H., Xiao, Y.P., Zhao, J., 2022. Donor growth stage and phenotype determine the effects of FMT on growth performance, gut microbiota development, and metabolic potentials in recipient pigs. Journal of Animal Science and Biotechnology, 13(5): 1483-1498.
6.Wang, X.F.*, Howe, S., Wei, X., Deng, F., Tsai, T., Chai, J., Xiao, Y., Yang, H., Maxwell, C.V., Li, Y., Zhao, J., 2021. Comprehensive cultivation of the swine gut microbiome reveals high bacterial diversity and guides bacterial isolation in pigs. mSystems, 6(4): e00477-21.
7.Liu, Z., Wu, H., Howe, S., Zuo, B., Tian, Y., Wang, X.F.*, Assress, H.A., Shang-Lun Lan, R., Mu, C., Xiao, Y., Huang, Y., Looper, M., Tsai, T., Zhao, J., 2026. Lactiplantibacillus plantarum promotes intestinal goblet cell differentiation via indole-3-lactic acid-AHR signaling in pigs. npj Biofilms and Microbiomes, doi: 10.1038/s41522-026-01085-6. Epub ahead of print. PMID: 42436183.
8.Li, Y., Wang, X.F.*, Wang, X.Q., Wang, J., Zhao, J., 2020. Life-long dynamics of the swine gut microbiome and their implications in probiotics development and food safety. Gut Microbes, 1-9.
9.Dou, C., Qu, H., Qin, Y., Wang, X.F.*, Yan, H., Li, R., Zhao, Y., Zhou, J., Wang, X., 2025. TSC2/mTORC1 integrates deoxynivalenol signals recognized by membrane receptors IR and EGFR to restrict intestinal stem cell function. Journal of Hazardous Materials, 494: 138769.
10.Cui, J., Tang, L., Li, Z., Wang, S., Zhou, J., Yan, H., Wang, X.F.*, 2025. Active factors in the adult pig colon: microbial transplantation versus supplementation with metabolites in weaned piglets. Microorganisms, 13(11): 2533.
11.Wang, X.F.*, Zong, X., Ye, M., Jin, C., Xu, T., Yang, J., Gao, C., Wang, X., Yan, H., 2024. Lysine distinctively manipulates myogenic regulatory factors and Wnt/Ca2+ pathway in slow and fast muscles, and their satellite cells of postnatal piglets. Cells, 13(7): 650.
12.Wang, X.F.*, Tsai, T., Wei, X., Zuo, B., Davis, E., Rehberger, T., Hernandez, S., Jochems, E.J., Maxwell, C.V., Zhao, J., 2021. Effect of Lacticylate and Bacillus subtilis on growth performance, peripheral blood cell profile, and gut microbiota of nursery pigs. Microorganisms, 9(4): 803.
13.Wang, X.F.*, Howe, S., Deng, F., Zhao, J., 2021. Current applications of absolute bacterial quantification in microbiome studies and decision-making regarding different biological questions. Microorganisms, 9(9): 1797.
14.Beane, K.E., Redding, M.C., Wang, X.F.*, Pan, J.H., Le, B., Cicalo, C., Jeon, S., Kim, Y.J., Lee, J.H., Shin, E.C., Li, Y., 2021. Effects of dietary fibers, micronutrients, and phytonutrients on gut microbiome: a review. Applied Biological Chemistry, 64(1): 1-18.
15.He, J., Xu, Z., Jiang, H., Chai, J., Wang, X.F.*, Deng, F., Zhao, J., Li, Y., 2026. Draft genome sequence of Clostridium thermobutyricum from the swine gut. Microbiology Resource Announcements, 15(5).
16.Dou, C., Qu, H., Qin, Y., Wang, X.F.*, Zhou, J., Wang, X., Yan, H., 2025. L-Glutamate enables the EGFR-MEK-ERK-mTFB2 axis to enhance mitochondrial biogenesis in intestinal stem cells. Stem Cell Research & Therapy, 16(1): 599.
17.Hu, T., Dou, C., Huang, Q., Wang, X.F.*, Yan, H., Zhou, J., Li, R., Zhao, Y., Wang, X., 2025. IP3R-dependent Ca2+ signaling in the endoplasmic reticulum is required for deoxynivalenol-induced intestinal stem cell injury. Biochemical Pharmacology, 242(Pt 3):117228.
18.Zan, G., Qu, H., Meng, J., Wang, X.F.*, Yan, H., Wang, X., Zhou, J., 2025. Matrine disturbs the Eimeria necatrix-induced loop of tuft cell-intestinal stem cell-goblet cell by inactivating IL-13/JAK2/STAT3 signaling. Poultry Science, 104(2): 104786.
19.Zan, G.X., Qu, H.Z., Li, X.Y., Peng, Q.L., Wang, X.F.*, Li, R.S., Zhao, Y.G., Yan, H.C., Zhou, J.Y., Wang, X.Q., 2025. Iturin A potentiates differentiation of intestinal epithelial defense cells by modulating Keap1/Nrf2 signaling to mitigate oxidative damage induced by heat-stable enterotoxin B. Antioxidants, 14(4).
20.Zan, G.X., He, H., Wang, X.F.*, Zhou, J.Y., Wang, X.Q., Yan, H.C., 2025. Morin reactivates Nrf2 by targeting inhibition of Keap1 to alleviate deoxynivalenol-induced intestinal oxidative damage. International Journal of Molecular Sciences, 26(3).
21.Zan, G., Wang, X.F.*, Yan, S., Qin, Y., Yao, L., Gao, C., Yan, H., Zhou, J., Wang, X., 2024. Matrine reduced intestinal stem cell damage in Eimeria necatrix-infected chicks via blocking hyperactivation of Wnt signaling. Phytomedicine, 128: 155363.
22.Qin, Y.C., Jin, C.L., Hu, T.C., Zhou, J.Y., Wang, X.F.*, Wang, X.Q., Kong, X.F., Yan, H.C., 2024. Early weaning inhibits intestinal stem cell expansion to disrupt the intestinal integrity of Duroc piglets via regulating the Keap1/Nrf2 signaling. Antioxidants, 13(10).
23.Zhou, J.Y., Xie, W.W., Hu, T.C., Wang, X.F.*, Yan, H.C., Wang, X.Q., 2024. Mulberry Leaf-Derived Morin Activates β-Catenin by Binding to Frizzled7 to Promote Intestinal Stem Cell Expansion upon Heat-Stable Enterotoxin b Injury[J]. Journal of Agricultural and Food Chemistry, 72(18): 10366-10375.
24.Lu, P.P., Zhong, C., Zhao, H.W., Li, F.Y., Wang, X.F.*, Wang, X.Q., Yan, H.C., Gao, C.Q., 2024. The amino acid sensor methionyl-tRNA synthetase is required for methionine-induced milk protein synthesis in a domestic pigeon model. British Journal of Nutrition, 132(3): 259-274.
25.Zhang, Y.R., Li, F.Y., Lu, Z.J., Wang, X.F.*, Yan, H.C., Wang, X.Q., Gao, C.Q., 2023. L-Malic acid facilitates stem cell-driven intestinal epithelial renewal through the amplification of β-catenin signaling by targeting Frizzled7 in chicks. Journal of Agricultural and Food Chemistry, 71(35): 13079-13091.
26.Zhu, C., Liang, S.J., Zan, G.X., Wang, X.F.*, Gao, C.Q., Yan, H.C., Wang, X.Q., Zhou, J.Y., 2023. Selenomethionine alleviates DON-induced oxidative stress via modulating Keap1/Nrf2 signaling in the small intestinal epithelium. Journal of Agricultural and Food Chemistry, 71(1): 895-904.
27.Chen, J., Li, Z., Wang, X.F.*, Fan, B., Deng, F., Yu, H.D., Ze, X., Zhu, L., Yin, Y., Chen, Y., Zhao, J., Yang, Y., Wang, X., 2022. Isomaltooligosaccharides sustain the growth of Prevotella both in vitro and in animal models. Microbiology Spectrum, 10(6): e02621-21.
28.Deng, F., Peng, Y., Zhang, Z., Howe, S., Wu, Z., Dou, J., Li, Y., Wang, X.F.*, Liang, Y., Zhao,J., and Li,Y. 2022. Weaning time affects the archaeal community structure and functional potential in pigs. Frontiers in Microbiology, 918.
29.Yang, Q., Liu, J., Wang, X.F.*, Robinson, K., Whitmore, M.A., Stewart, S.N., Zhao, J., Zhang, G., 2021. Identification of an intestinal microbiota signature associated with the severity of necrotic enteritis. Frontiers in Microbiology, 12.
30.Deng, F., Li, Y., Peng, Y., Wei, X., Wang, X.F.*, Howe, S., Yang, H., Xiao, Y., Li, H., Zhao, J., Li, Y., 2021. The diversity, composition, and metabolic pathways of archaea in pigs. Animals, 11(7): 2139.
31.Wang, Q., Chen, X., Hu, H., Wei, X., Wang, X.F.*, Peng, Z., Ma, R., Zhao, Q., Zhao, J., Liu, J., Deng, F., 2021. Structural changes in the oral microbiome of the adolescent patients with moderate or severe dental fluorosis. Scientific Reports, 11(1): 1-9.
32.Deng, F., McClure, M., Rorie, R., Wang, X.F.*, Chai, J., Wei, X., Lai, S., Zhao, J., 2019. The vaginal and fecal microbiomes are related to pregnancy status in beef heifers. Journal of Animal Science and Biotechnology, 10(1), pp.1-13.
33.Tsai,T., Sales,M.A., Kim,H., Erf,G.F., Vo,N., Carbonaro,F., VanDerMerwe,M., Kegley,E.B., Buddington,R., Wang,X.F.* and Maxwell,C.V., J.Zhao, 2018. Isolated rearing at lactation increases gut microbial diversity and post-weaning performance in pigs. Frontiers in Microbiology, 9.
（1）ZHAO Jiangchao, WANG Xiaofan, TSAI Tsungcheng, MAXWELL Charles V. Swine origin probiotics that promote health and growth performance in pigs. Patent No.: US 12,220,435 B2.
（2）王晓帆，宋晓凤，赵江潮，王修启，金成龙. α-酮丁酸在促进骨骼肌纤维类型从快肌转化为慢肌中的应用：中国，ZL 202511571256.2[P]. 2026-08-25.
（3）赵江潮，张翔宇，王晓帆，全建平，李龚. 一株解没食子酸链球菌及其在制备抗沙门氏菌感染制剂中的应用：中国，ZL202610163513.7[P]. 2026-05-01.
（4）赵江潮，张翔宇，黄咏诗，王晓帆，全建平，李龚. 一株非解乳糖链球菌及其在制备抗沙门氏菌感染制剂中的应用：中国，ZL202610614956.3[P]. 2026-06-18.
申请发明专利：
（1）王晓帆，王双，李子轩，唐烈发，王修启，赵江潮. 瘤胃球菌及其体外纯培养代谢上清液在促进仔猪肠道发育中的应用. 申请号：CN202510983175.7
（2）王晓帆，崔建昊，赵江潮，王修启，周加义. 埃氏巨球形菌在促进仔猪肠道发育中的应用. 申请号：CN202510918587.2
（3）王晓帆，项轩，赵江潮，全建平，李龚. 一种评估猪饲粮纤维消化潜力的微生态标志物及其应用. 申请号：CN2026114167385.5
（4）赵江潮，王晓帆，王雨婷，全建平，李龚. 解没食子酸链球菌在制备促进猪胆汁酸代谢以及油脂乳化的制剂中的应用. 申请号：CN 202610745204.0
（5）高春起，冯钰晴，张盛，卢铸金，曾楠，王修启，王晓帆，严会超. 一种用于培养鸡肠道干细胞的培养基及其应用. 申请号：CN202311491784.8
（6）王修启，周加义，昝庚秀，梁少杰，朱超，王晓帆，高春起，严会超. 一种筛选能够缓解呕吐毒素诱导的肠道损伤的药物的方法及试剂盒. 申请号：CN202311738754.2
本科课程：《饲料卫生与安全》、《宠物鉴赏与饲养》
1. 2026届优秀毕业生：宋晓凤
2. 2026年度国家奖学金：陈惠茹（博一，2026级博士生）、崔健昊（研三，2024级硕士生）、刘星琦（研二，2025级硕士生）
3. 2026年本科生推免：周涛（大四，2022级本科生），推免至浙江大学
