目录
更新日期:2020年9月8日
姓 名 马静云 性 别
出生年月 1974年4月 籍贯 广东普宁市
民 族 汉族 政治面貌 民盟
最后学历 博士研究生毕业 最后学位
技术职称 教授 导师类别 博、硕导
行政职务 系主任 Email majy2400@scau.edu.cn
工作单位 动物科学学院 邮政编码 510642
通讯地址
单位电话 020-85280283
个人主页 http://dongke.scau.edu.cn/a/szdw/sssds/2015/0625/115.html
个人简介
女,1974年4月17日生,广东普宁市人,现在华南农业大学动物科学学院动物生产系主任,教授,博士、硕士生导师。专业领域:动物健康养殖与安全生产;研究方向:动物免疫与生物安全、动物疫病综合防控。
工作经历
2003.7-2005.12:  华南农业大学动物科学学院,讲师
2005.12-2016.12 :华南农业大学动物科学学院,副教授,硕士生导师
2012.10-2013.10:美国肯塔基州立大学访学一年
2016.12-至今:华南农业大学动物科学学院,教授
教育经历
1993.9-1998.6: 华南农业大学兽医系(农学学士)

1998.9-2003.6 华南农业大学动物科学学院预防兽医学方向(农学博士,硕博连读)
获奖、荣誉称号
1、应用LUX新型实时核酸扩增技术建立多种动物疫病病原快速检测方法研究,2011年获广东检验检疫局科技兴检奖二等奖一项
2、应用LUX新型实时核酸扩增技术建立多种动物疫病快速检测方法,2013年获广东科技进步奖三等奖一项。
3、人畜共患重大动物病毒性传染病诊断检测方法与应用,广东省科学技术三等奖
4、水禽常发病防控技术体系推广与应用,广东省农业技术推广二等奖
研究领域
动物健康养殖与安全生产、动物免疫与安全生产、分子病毒学、动物疫病综合防控等
科研项目
承担及参与课题

(1) 广东省基础与应用基础研究基金委员会,广东省自然科学基金-面上项目,2020A1515010220,SADS-CoV上调宿主TN和ITGA7表达促进大肠杆菌粘附的分子机制研究,2019/10-2022/9, 10万元,在研,参加
(2) 广东省基础与应用基础研究基金委员会,广东省自然科学基金-面上项目,2020A1515010295,miR-1285/DDX3X互作在SVA感染PK-15细胞中介导RIG-I信号通路调控IFN-β表达的分子机制,2019/10-2022/9, 10万元,在研,参加
(3) 广东省科技厅,广东省科技厅重点领域研发项目,201902112019B020211005,非洲猪瘟精准检测技术研究及应用,2019-06至2022-05,40万元,在研,参加
(4) 广州市科学技术局,广州市科技计划项目,201904010433,猪急性腹泻综合症冠状病毒N蛋白调控宿主天然免疫的分子机制研究,2019-04至2022-03,20万元,在研,主持
(5) 广东省农业厅,广东省农业科技推广专项资金项目,猪急性腹泻综合冠状病毒(SADS-CoV)流行病学调查及致病机理研究,2018-09至2020-09,40万元,在研,主持
(6) 国家科技部,十三五国家重点研发项目子课题,2016YFD0501304,畜禽病原菌耐药性数据库建设及预警技术研究,2016-07至2020-12,65万元,在研,主持
(7) 国家自然科学基金委员会,青年基金项目,31502144,类胰岛素生长因子(IGFs)促鱼类卵巢成熟的功能研究,2016-01至2018-12,24万,已结题,参加
(8) 广东省基础与应用基础研究基金委员会,广东省自然科学基金-面上项目,2015A030313409,类胰岛素生长因子IGF促鱼类卵巢成熟的功能研究,2015-08至2018-08,10万元,已结题,参加
(9) 广东省科技厅,广东省科技厅科技攻关项目,2014A020208093,奶牛乳房炎致病性细菌噬菌体的分离及裂解酶的表达应用研究,2015-01至2016-12,20万元,已结题,主持
(10) 广州市科学技术局,广州市科技计划项目,2013J4100051, 猪病毒性腹泻流行病学调查及病毒新型口服疫苗的研究,2013-01至2014-12,8万元,已结题,主持
(11) 广东省科技厅,广东省科技厅产学研项目,2011B090400414 ,以乳酸乳球菌、酵母杆菌为载体的猪病毒性腹泻新型口服粘膜疫苗的研究与应用 ,2011-7至2013-12, 30万元,已结题,主持
(12) 广东省科技厅,广东省科技厅科技攻关项目,2011B020306005,猪主要细胞因子在乳球菌的表达及作为口服疫苗免疫佐剂的研究 ,2012-01至2013-12,8万元,已结题,主持
(13) 国家自然科学基金委员会,面上项目,31072152,与J亚型禽白血病肿瘤发生发展相关的microRNA的鉴定与功能分析,2010-08至2013-12,33万元,已结题,参加
(14) 广东省科技厅,广东省科技攻关重大专项,2008A02040002, 高致病性蓝耳病综合防制技术研究,2008-01至2011-12,10万元,已结题,子课题负责人
(15) 国家科技部,国家公益性行业科研专项,2007GYJ019,动物检疫病毒恢复系统、分子资源库及其测定,2007-12至2012-12,40万元,已结题,副主持
发表论文
近5年发表主要论文
(1) Yun Sun#, Jian Cheng#, Ying Luo, Xiaoling Yan, Zixian Wu, Lili He, Yaorong Tan, Zhihai Zhou, Qianniu Li, Ling Zhou, Ruiting Wu, Tian Lan∗, Jingyun Ma∗, Attenuation of a virulent swine acute diarrhea syndrome coronavirus strain via cell culture passage, Virology, 2019, 538:61-70.
(2) Lingzhou, Qianniu Li, Jiangnan Su, Guihua Chen, Zixian Wu, Ying Luo, Ruiting Wu, Yuan Sun, Tian Lan, Jingyun Ma*, The re-emerging of SADS-CoV infection in pig herds in Southern China, Transboundary and Emerging Diseases, 2019,66(2): 687-695.
(3) Xiaoling Yan#, Yiyi Li, Lili He, Jiaoling Wu, Xiaoyu Tang, Guihua Chen, Kaijie Mai, Ruiting Wu, qianniu Li, Yonghui Chen, Yuan Sun, Jingyun Ma*. 12 novel atypical porcine pestivirus genomes from neonatal piglets with congenital tremors: A newly emerging branch and high prevalence in China. Virology, 2019, 533: 50-58.
(4) Jiaoling Wu #, Kaijie Mai, Di Li, Ruiting Wu, Zixian Wu, Xiaoyu Tang, Qianniu Li, Yuan Sun, Tian Lan, Xiangbin Zhang, Jingyun Ma*. Expression profile analysis of 5-day-old neonatal piglets infected with porcine Deltacoronavirus. BMC Vet Res, 2019, 15(1):117.
(5) Xiaoyu Tang, Tian Lan, Ruiting Wu, Zhihai Zhou, Yuqi Chen, Yuan Sun, Yaoyao Zheng, Jingyun Ma*. Analysis of long non-coding RNAs in neonatal piglets at different stages of porcine deltacoronavirus infection, BMC Vet Res, 2019, 15(1):111.
(6) Lingzhou#, Qianniu Li, Jiangnan Su, Guihua Chen, Zixian Wu, Ying Luo, Ruiting Wu, Yuan Sun, Tian Lan, Jingyun Ma*, The re-emerging of SADS-CoV infection in pig herds in Southern China. Transboundary and Emerging Diseases, 2019. doi: 10.1111/tbed.13270.
(7) Yuan Sun#, Jian Cheng, Ruiting Wu, Zixian Wu, Chen JW, Ying Luo, Qingmei Xie, Jingyun Ma*, Phylogenetic and Genome Analysis of 17 Novel Senecavirus A Isolates in Guangdong Province, 2017. Front Vet Sci. 2018, 5:314.
(8) Peng Zhou#, Hang Fan#, Tian Lan#, Xinglou Yang, Weifeng Shi, Wei Zhang, Yan Zhu, Yawei Zhang, Qingmei Xie, Shailendra Mani, Xiaoshuang Zheng, Bei Li, Jinman Li, Hua Guo, Guangqian Pei, Xiaoping An, Junwei Chen, Ling Zhou, Kaijie Mai, Zixian Wu, Di Li, Danielle E. Anderson, Libiao Zhang, Shiyue Li, Zhiqiang Mi, Tongtong He, Feng Cong, Pengju Guo, Ren Huang, Yun Luo, Xiangling Liu, Jing Chen, Yong Huang, Qiang Sun, Xiang-lilan Zhang, Yuanyuan Wang, Shaozhen Xing, Yanshan Chen, Yuan Sun, Juan Li, Peter Daszak*, Linfa Wang*, Zhengli Shi*, Yigang Tong*, Jingyun Ma*, Fatal Swine Acute Diarrhea Syndrome caused by an HKU2-related Coronavirus of Bat Origin,  Nature, 2018, 556(7700): 255-258.
(9) Ling Zhou#, Yuan Sun, Tian Lan, Rui-Ting Wu, Jun-Wei Chen, Zi-Xian Wu, Qing-Mei Xie, Xiang-Bin Zhang*, Jingyun Ma*, Retrospective detection and phylogenetic analysis of swine acute diarrhea syndrome coronavirus in pigs in southern China. Transboundary and Emerging Diseases. 2018, 66 (2): 687-695.
(10) Ling Zhou#, Yuan Sun, Jiao-ling Wu, Kai-jie Mai, Gui-hua Chen, Zi-xian Wu, Yang Bai, Di Li, Zhi-hai Zhou, Jian Chen, Rui-ting Wu, Xiang-bin Zhang, Jingyun Ma*, Development of a TaqMan-based real-time RT-PCR assay for the detection of SADS-CoV associated with severe diarrhea disease in pigs. Journal of Virological Methods. 2018, 255: 66-70.
(11) Huanan Wang#, Feng Cong, Fanwen Zeng, Yuexiao Lian, Xiangnan Liu, Manlin Luo, Pengju Guo, Jingyun Ma*, Development of a real time reverse transcription loop-mediated isothermal amplification method (RT-LAMP) for detection of a novel swine acute diarrhea syndrome coronavirus (SADS-CoV). Journal of Virological Methods. 2018, 260: 45-48.
(12) Gui-hua Chen#, Xiao-yu Tang, Yuan Sun, Ling Zhou, Di Li, Yang Bai, Kai-jie Mai, YY Li, Qi-wen Wu, Jingyun Ma*, Development of a SYBR green-based real-time quantitative PCR assay to detect PCV3 in pigs. Journal of Virological Methods. 2018, 251: 129-132.
(13) Kaijie Mai#, Di Li, Jiaoling Wu, Zixian Wu, Jian Cheng, Lili He, Xiaoyu Tang, Zhihai Zhou, Yuan Sun, Jingyun Ma*, Complete Genome Sequences of Two Porcine Deltacoronavirus Strains, CHN-GD16-03 and CHN-GD16-05, Isolated in Southern China. Genome Announcements. 2018, 6(4): e01545-17.
(14) X. Zhao#, Q. Wu, Y. Bai, G. Chen, L. Zhou, Z. Wu, H. Yang, J. Ma*, Phylogenetic and genome analysis of 17 novel senecavirus A isolates in Guangdong provience,2017. Transboundary and Emerging Diseases. 2017.
(15) G. H. Chen#, K. J. Mai1, L. Zhou, R. T. Wu, X. Y. Tang, J. L. Wu, L. L. He, T. Lan, Q. M. Xie, Y. Sun*, J. Y. Ma*, Detection and genome sequencing of porcine circovirus 3 inneonatal pigs with congenital tremors in South China,Transbound Emerg Dis. 2017, 64(6): 1650-1654.
(16) Xiaoya Zhao#, Zhili Li, Xiduo Zeng, Guanqun Zhang, Jianqiang Niu, Baoli Sun, Jingyun Ma*, Sequence analysis of the spike gene of Porcine epidemic diarrhea virus isolated from South China during 2011-2015, J Vet Sci 2017, 18(2), 237-243.
(17) Qiwen Wu#, Zhili Li, Guanqun Zhang, Jianqiang Niu, Xiduo Zeng, Baoli Sun, Jingyun Ma*, Genetic diversity and phylogenetic analysis of porcine reproductive and respiratory syndrome virus in southern China from 2007 to 2014,J Vet Sci 2017, 18(3): 317-326.
(18) K. Mai#, J. Feng, G. Chen, D. Li, L. Zhou, Y. Bai, Q.Wu, J.Ma*. The detection and phylogenetic analysis of porcine deltacoronavirus from Guangdong Province in Southern China, Transbound Emerg Dis. 2017, 65(1): 166 - 173.
(19) Qiwen Wu#, Xiaoya Zhao, Yang Bai, Baoli Sun, Qingmei Xie, Jingyun Ma*, The First Identification and Complete Genome of Senecavirus A Which Affected Pig with Idiopathic Vesicular Disease in China, Transboundary and Emerging Diseases, 2016 Aug 18.
(20) Jindai Fan#, Zhiliang Zeng#, Kaijie Mai, Yu Yang, Jiaqi Feng, Yang Bai, Baoli Sun, Qingmei Xie, Yigang Tong*, Jingyun Ma*, Preliminary treatment of bovine mastitis caused by Staphylococcus aureus, with trx-SA1, recombinant endolysin of S. aureus bacteriophage IME-SA1, Veterinary Microbiology. 2016, 191:  65-71.
(21) Qiwen Wu#, Xiaoya Zhao, Yanshan Chen, Xiaoming He, Guanqun Zhang, Jingyun Ma*. Complete Genome Sequence of Seneca Valley Virus CH-01-2015 Identified in China, Genome Announcements. 2016, 4(1): e01509-15.
(22) Fan J#, Zeng X, Zhang G, Wu Q, Niu J, Sun B, Xie Q, Ma J*. Molecular characterization and phylogenetic analysis of pseudorabies virus variants isolated from Guangdong Province of Southern China during 2013-2014, J Vet Sci. 2016, 17(3): 369-375.
(23) Wen Hui Lu#, Hein Min Tun, Bao Li Sun, JianYui Mo, Qing Feng Zhou,  Yu Xiu Deng, Qing Mei Xie , Ying Zuo Bi, Frederick Chi-Ching Leung, Jing Yun Ma*, Re-emerging of porcine respiratory and reproductive syndrome virus (lineage 3) and increased pathogenicity after genomic recombination with vaccine variant, Veterinary Microbiology. 2015, 175(2-4): 332-40.
(24) Wenhui Lu#, Baoli Sun, Jianyue Mo, Xiduo Zeng, Guanqun Zhang, Lianxiang Wang, Qingfeng Zhou, Ling Zhu, Zhili Li, Qingmei Xie, Yinzuo Bi,  Jingyun Ma*. Attenuation and Immunogenicity of a Live HighPathogenic PRRSV Vaccine Candidate with a 32-Amino AcidDeletion in the NSP2 Protein, Journal of Immunology Research,Volume 2014: 810523.
(25) Zhili Li#, Feng Chen, Yao Yuan, Xiduo Zeng, Zhongyan Wei, Ling Zhu, Baoli Sun, Qingmei Xie, Yongchang Cao, Chunyi Xue, Jingyun Ma*, Yingzuo Bee*. Sequence and phylogenetic analysis of nucleocapsid genes of porcine epidemic diarrhea virus (PEDV) strains in China. Archives of Virology, 2013,158(6): 1267–1273.
(26) Guanqun Zhang#, Wenhui Lu, Yanshan Chen, Ling Zhu, Zhongyan Wei, Zhili Li, Baoli Sun, Qingmei Xie, Yingzuo Bi, Jingyun Ma*. Complete Genome Sequence of Two Variant Porcine Reproductive and Respiratory Syndrome Viruses Isolated from Vaccinated Piglets. Journal of Virology, 2012, 86(20): 11396-11397.
(27) Zhong-yan Wei#, Wen-hui Lu, Zhi-li Li, Jian-yue Mo, Xi-duo Zeng, Zhi-liang Zeng, Bao-li Sun, Feng Chen, Qing-Mei Xie, Ying-zuo Bee*, Jing-yun Ma*.  Complete Genome Sequence of a Novel Porcine Epidemic Diarrhea Virus Strain GD-1 in China. Journal of Virology, 2012, 86(24): 13824-13825.
(28) YuYun Gao#, QingMei Xie, Ling Jin, BaoLi Sun, Jun Ji, Feng Chen, JingYun Ma*, YingZuo Bi*. Supplementation of xanthophylls decreased proinflammatory and increased anti-inflammatory cytokines in hens and chicks. British Journal of Nutrition, 2012, 108(10): 1746-55.
(29) Lu Wenhui#, Wei Zhongyan, Zhang Guanqun, Li Zhili, Ma JingYun*, Xie Qingmei, Sun Baoli, Bi Yingzuo. Complete Genome Sequence of a Novel Variant Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Strain: Evidence for Recombination between Vaccine and Wild-Type PRRSV Strains. Journal of Virology, 2012, 86(17): 9543.
(30) Zhi-Li Li#, Ling Zhu, Jing-Yun Ma*, Qing-Feng Zhou, Yan-Hua Song, Bao-Li Sun, Rui-Ai Chen, Qing-Mei Xie, Ying-Zuo Bee*. Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field strains in south China. Virus Genes, 2012, 45(1): 181-185.
(31) Ling Zhu#, Guanqun Zhang, Jingyun Ma*, Xiaoming He, Qingmei Xie, Yingzuo Bee, Shanzhong Gong. Complete genomic characterization of a Chinese isolate of porcine reproductive and respiratory syndrome virus, Veterinary Microbiology, 2011, 147 (3-4): 274-282.
中文:
1、唐晓钰,周芝海,吴芮庭,陈雨琪,郑瑶瑶,苏江南,马静云*,猪 A 型塞内卡病毒感染诱导猪肾细胞(PK-15)长链非编码 RNA 差异表达谱的分析,中国预防兽医学报,2020,42(1):6-11
2、谭耀荣,李 迪,郑瑶瑶,陈雨琪,苏江南,燕晓玲,马静云*,一株猪源肺炎克雷伯氏菌的分离鉴定及耐药性、耐药基因的检测, 黑龙江畜牧兽医科技,2020( 06) : 57-62
3、周芝海,谭耀荣,郑瑶瑶,曾繁文,麦凯杰,马静云*,猪急性腹泻综合征冠状病毒核衣壳蛋白的原核表达及多克隆抗体的制备,中国兽医科学,2019 49(09):1179- 1186
4、陈桂华,孙媛,周玲,李迪,白杨,麦凯杰,高金铭,马静云*,猪圆环病毒3型Cap蛋白的表达纯化及单克隆抗体的制备,中国兽医科学,2019,1,13-19
5、白杨,伍绮文,陈桂华,周玲,李怡昀,周雯馨,马若瑶,马静云*,塞内加谷病毒VP1蛋白的表达纯化及鉴定,中国兽医科学,2017,47(04),500-507
6、赵晓亚,伍绮文,伍子娴,陈桂华,白杨,马静云*,国内首株猪塞内加谷病毒(Seneca Valley virus)的分离鉴定,中国预防兽医学报,2016,38(11),839-843
7、范锦戴,陈慧敏,马保华,罗敏瑜,曾志良,马静云*,副猪嗜血杆菌纳米PCR检测方法的建立,中国兽医科学,2015,45(10),1043-1046
8、范锦戴,申晓晨,马若瑶,冯嘉琪,麦凯杰,曾志良,马静云*,一株奶牛乳腺炎金黄色葡萄球菌噬菌体的分离鉴定及其生物学特性的研究,中国兽医科学,2015,45(12),1236-1241
9、磨健悦,孙宝丽,魏钟艳,曾喜多,曾志良,谢青梅,毕英佐,马静云*,猪流行性腹泻病毒COE基因的原核表达及其表达产物的生物活性分析,中国兽医科学,2015,45(05),503-508
10、曾喜多,魏钟艳,李智丽,孙宝丽,谢青梅,毕英佐,马静云*,猪流行性腹泻病毒抗体间接ELISA检测方法的建立与应用,华南农业大学学报,2015,36(4),16-20
11、磨健悦,孙宝丽,陆金成,曾喜多,谢青梅,毕英佐,马静云*,猪IL–6基因在毕赤酵母中的表达及生物活性鉴定,黑龙江畜牧兽医科技版, 2014,(11),86-89
出版专著和教材
参与编写学术专著《口蹄疫》(2005年4月广东科技出版社出版)。
科研创新
专利号及申请号(排名第一)
(1) 马静云;磨健悦;曾喜多;孙宝丽;毕英佐;一种可口服的猪流行性腹泻病毒亚单位疫苗的制备方法, 2015-2-18, 中国, CN201410533507.3.
(2) 马静云;李智丽;曾喜多;魏钟艳;孙宝丽;谢青梅;毕英佐;一种分泌表达PEDV核心抗原COE蛋白重组乳酸乳球菌及其制备方法和应用, 2014-6-30, 中国, ZL201410303777.5.
(3) 马静云;袁尧;胡文峰;李智丽;曾喜多;孙宝丽;毕英佐;一种表面展示PEDV核心抗原COE蛋白重组毕赤酵母菌的制备方法, 2014-5-8, 中国, ZL201410192205.4.
(4) 马静云,赵晓亚,陈桂华,伍绮文;一种塞内加谷病毒实时荧光PCR检测引物及试剂盒;2016-6-1,中国,ZL201610379248.2.
(5) 马静云,郭鹏举,朱余军,伍绮文;一种鉴别猪口蹄疫病毒与塞内加谷病毒的HRM检测引物及方法,2016-6-22,中国,ZL201610126868.5.
(6) 马静云,范锦戴,麦凯杰,冯嘉琪;一种可以裂解大肠杆菌及沙门氏菌的噬菌体裂解酶的制备方法,2016-12-12,中国,201611139628.5.
(7) 马静云;蓝天;孙媛;陈桂华;一种检测猪圆环病毒3型病毒的引物对、方法试剂盒,2017-4-25, 中国,201710277024.5
(8) 马静云;周玲;孙媛;一种新型猪急性腹泻综合征冠状病毒的荧光定量PCR检测引物及试剂盒,2017-10-27, 中国,201710243135.4
(9) 马静云;周玲;蓝天;孙媛;李倩妞;一种基于实时荧光逆转录重组酶聚合酶核酸扩增技术检测SADS-CoV的引物和试剂盒,2019-12-13,中国,201911228022.7
(10) 马静云;周玲;陈咏辉;卢先东;方雪恩;刘艳红;孔继烈;一种用于检测PEDV的离心式微流控芯片结合环介导等温扩增技术的引物和试剂盒,2019-12-13,中国,201911284458.3
教学活动
主讲本科生课程:“畜牧微生物学”、“基因工程原理”

主讲硕士、博士生课程:“基因工程实验技术”、“动物营养与免疫专题”
参与研究生课程:“应激免疫学”、畜禽健康养殖与安全生产专题“
指导学生情况
2006年获硕士导师资格,07年开始招收硕士研究生,17年获博士导师资格。目前已经培养毕业研究生25名,在读研究生8名,2016年、2017年、2018年、2020年分别有1名、1名、3名、2名研究生获“优秀毕业论文奖”及“优秀毕业研究生”称号,其中一名还获得广东省优秀研究生称号;5人获国家奖学金。2011年有一名研究生获全奖到墨尔本大学攻读博士学位;2017年一名研究生获全奖到加拿大曼尼托巴大学攻毒博士学位。