目录
祝钦泷   更新日期: 2020年9月7日
祝钦泷,男,汉族,1979年3月生,重庆人,群众,博士研究生学历,农学博士学位学位,教授,硕导。
工作单位   生命科学学院/亚热带农业生物资源保护与利用国家重点实验室
邮政编码  510642
通讯地址  广州市华南农业大学科技楼512
单位电话  020-85288395
邮箱地址  zhuql@scau.edu.cn
个人主页  http://life.scau.edu.cn/nav-staff-30003615.asp
个人简介
祝钦泷,博士,青年教授,“广东特支计划”科技创新青年拔尖人才。就职于华南农业大学生命科学学院/亚热带农业生物资源保护与利用国家重点实验室。主要从事植物合成生物学与基因编辑技术研究。 开发了高效多基因叠加系统TGSII, 多基因单碱基编辑系统,培育了首个高抗氧化活性的胚乳富含花青素的“紫晶米”和首个胚乳合成高级类胡萝卜素虾青素的“赤晶米”。 已在Molecular Plant (2篇封面文章),Plant Biotechnology Journal, Journal of Genetics Genomics,Planta,Gene等国际知名刊物发表SCI论文20多篇,累计SCI影响因子超过120,Google Scholar总引1344次。主持国家自然基金项目3项、省部级课题5项。申请中国发明专利7项。作为第一导师指导学生获得2016 iGEM(国际基因工程机器)大赛全球金奖与4个单项奖(包括全球总成绩第三“Second Runner-Up”,以及首个最佳植物合成生物学奖“Best Plant Synthetic Biology”等单项奖)。先后担任《Biotechnology Advance》,《Molecular Plant》, 《Plant Biotechnology Journal》等国际著名学术期刊特邀审稿人。国际期刊《Frontiers in Genome editing》编辑。
工作经历
2019.10- 至今  :华南农业大学生命科学学院/亚热带农业生物资源保护与利用国家重点实验室,青年教授
2016.12- 2019.9:华南农业大学生命科学学院/亚热带农业生物资源保护与利用国家重点实验室,副研究员
2017.12- 2018.11 :美国康奈尔大学(Cornell University)/Robert W. Holley Center,Plant Science, 客座副教授(Visiting Associate Professor)
2011.07-2016.11  :华南农业大学生命科学学院,助理研究员
2007.08-2011.06:华南农业大学生命科学学院,生物学博士后流动站,博士后
教育经历
2004-09至2007-06,西南大学, 园艺学(花卉分子育种)专业,获农学博士学位;
2001-09至2004-07,西南农业大学(现西南大学),细胞生物学专业,获理学硕士学位;
1997-09至2001-06,四川畜牧兽医学院(现西南大学荣昌校区),动物科学专业,获农学学士学位;
获奖荣誉
8. 2019年第十三届中国生物工程学会年会暨全国生物技术大会,青年优秀论文特等奖(唯一);
7. 2019年第二届分子植物育种大会优秀墙报奖;
6. 2019年中国生物工程学会第四届青年科技论坛优秀墙报奖;
5. 2018年第四届“药食同源与植物代谢国际研讨会”优秀墙报(二等奖);
4. 2017年第十届大北农科技奖基因工程奖(第6/12);
3. 2017 the Best POSTER AWARD, the 4th ICPM (International Conference on Plant Metabolism),CSPB;
2. 2009年第六届中国科协期刊优秀学术论文(三等奖);
1. 2007年郑集-张昌颖青年优秀论文奖,CSBMB (The Chinese Society of Biochemistry and Molecular Biology);
社会、学会及学术兼职
1.中国生物化学与分子生物学学会(CSBMB)会员;
2.中国植物生理与植物分子生物学学会(CSPB)会员;
3.中国生物工程学会(CSBT)会员;
4.国际学术期刊《Biotechnology Advance》, 《Molecular Plant》, 《Plant Biotechnology Journal》等10多个期刊的特邀审稿人;                                              
5.国际期刊《Frontiers in Genome editing》编辑。
研究领域
1. 植物基因工程技术系统(多基因叠加载体系统和基因组编辑CRISPR/Cas9系统)的开发与应用;
2. 植物代谢工程与合成生物学;
3. 作物营养物质强化与功能性种质创新;
4. 植物类黄酮和类胡萝卜素代谢调控;
科研项目
主持
8. 国家自然科学基金面上项目(31971915),2020.1-2023.12,主持;
7. 转基因重大专项“转基因新技术新方法”子课题(2016ZX08010001-008),2019.1-2020.12,主持;
6. 国家自然科学基金面上项目(31771740),2018.1-2021.12, 主持;
5. 广东省公益研究与能力建设项目(2016A020210084 ),2016.1-2018.12, 主持;
4. 国家自然科学基金青年基金(31000698),2011.1-2013.12, 主持;;
3. 广东省自然科学基金(10451064201005422),2010.10-2012.10, 主持;
2. 国家“863”计划课题“高效、安全转基因技术的创建”子课题(2007AA10Z184),2007.9-2010.8, 主持;
1. 博士后科学基金(20070420787),2007.9-2010.12, 主持。

主要参加课题
6. 广东省公益研究与能力建设项目(2015B020201002),2015.7-2018.6, 参加,排名第2/9;
5. 国家自然科学基金重点项目(C130401),2015.1-2017.12,参加, 排名第2/5;
4. 转基因重大专项“转基因新技术新方法”子课题(2012AA10A303),2012.6-2014.12.,参加,排名第2/10;
3. 国家自然科学基金青年基金(31401449),2015.1-2017.12,参加,排名第3/6;
2. 国家自然科学基金重点项目(31230052),2013.1-2017.12,参加, 排名第5/10;
1. 广东省自然科学基金(2016A030310443),2016.1-2019.6,参加, 排名第2/5;
发表论文
(主要文章,*Corresponding author)  
28. Gong Q,Wang B, Lu X, Tan J, Hou Y, Liu T, Liu Y-G*, Zhu Q*. Nicking Endonuclease-Mediated Vector Construction Strategies for Plant Gene Functional Research. Plants, 2020, 9(9): 1090. (IF2019=2.762)
27. Zeng D, Liu T, Ma X, Wang B, Zheng Z, Zhang Y, Xie X, Yang B, Zhao Z, Zhu Q*, Liu Y-G*. Quantitative regulation of Waxy expression by CRISPR/Cas9-based promoter and 5'UTR-intron editing improves grain quality in rice. Plant Biotechnology Journal, 2020, doi:10.1111/pbi.13427. (IF2019=8.154)
26.Tan J, Zhao Y, Wang B,  Hao Y, Wang Y, Li Y, Luo W, Zong W, Li G, Chen S, Ma K, Xie X, Chen L, Liu Y‐G*, Zhu Q*. Efficient CRISPR/Cas9-based plant genomic fragment deletions by microhomology-mediated end joining. Plant Biotechnology Journal, 2020, doi:10.1111/pbi.13390.(IF2019=8.154)
25.Wang B, Fang R, Chen F, Han J, Liu Y-G, Chen L*, Zhu Q*. A novel CCCH‐type zinc‐finger protein SAW1 activates OsGA20ox3 to regulate gibberellin homeostasis and anther development in rice, Journal of Integrative Plant Biology, 2020, doi: 10.1111/jipb.12924. (IF2019=4.885)
24. Hao Y, Zong W, Zeng D, Han J, Chen S, Tang J, Zhao Z, Li X, Ma K, Xie X, Zhu Q, Chen Y, Zhao X, Guo J*, Liu Y-G*. Shortened snRNA promoters for efficient CRISPR/Cas-based multiplex genome editing in monocot plants. Science China Life Sciences, 2020, https://doi.org/10.1007/s11427-019-1612-6. (IF2019=4.611).
23. Zeng D, Li X, Huang J, Li Y, Cai S, Yu W, Li Y, Huang Y, Xie X, Gong Q, Tan J, Zheng Z, Guo M, Liu Y-G*, Zhu Q*. Engineered Cas9 variant tools expand targeting scope of genome and base editing in rice. Plant Biotechnology Journal. 2020, 18(6):1348-1350. (IF2019=8.154)
22. Zhu Q, Wang B, Tan J, Liu T, Li L, Liu Y-G*. Plant Synthetic Metabolic Engineering for Enhancing Crop Nutritional Quality. Plant Communications. 2020, 1, 100017.
21. Tan J, Gong Q, Yu S, Hou Y, Zeng D, Zhu Q*, Liu Y-G*. A modified high-efficiency thermal asymmetric interlaced PCR method for amplifying long unknown flanking sequences. Journal of Genetics and Genomics, 2019,46(7):363-366. (IF2019=5.065)
20. Ma K, Han J, Hao Y, Yang Z, Chen J, Liu Y-G, Zhu Q*, Chen L*.  An effective strategy to establish a male sterility mutant mini-library by CRISPR/Cas9 knockout of anther-specific genes in rice. Journal of Genetics and Genomics, 2019,46(5): 273-275. (IF2019=5.065)
19.Zhu Q, Zeng D, Yu S, Cui C, Li J, Li H, Chen J, Zhang R, Zhao X, Chen L, Liu Y-G*. From Golden Rice to aSTARice: Bioengineering Astaxanthin Biosynthesis in Rice Endosperm.Molecular plant, 2018,11(12): 1440-1448.(“赤晶米”,封面文章)(IF2018=10.812).
Highlights:
(1) Chen WC, Lu S. From golden rice to aSTARice, more than just two steps forward in a pathway. Science China Life Sciences, 2019, 62, 280-281.
(2) Astaxanthin Rice, a new biofortified crop germplasm developed by multigene metabolic engineering. SCIENCE FOUNDATION IN CHINA. 2018, 26 (4): 21.  
(3) 朱丽, 钱前. 虾青素功能米: 生物强化新思路, 优质米培育新资源. 植物学报,2019,54 (1): 4-8.
(4) 变红的大米.《十万个为什么:探索版》.2019, 4: 38-40.
18. Xie Y, Zhang Y, Han J, Luo J, Li G, Huang J, Wu H, Tian Q, Zhu Q, Chen Y, Kawano Y, Liu Y-Guang, Chen L*. The Intronic cis Element SE1 Recruits trans-Acting Repressor Complexes to Repress the Expression of ELONGATED UPPERMOST INTERNODE1 in Rice. Molecular plant, 2018, 11(5):720-735.(IF2018=10.812)
17. Shen R, Wang L, Liu X, Wu J, Jin W, Zhao X, Xie X, Zhu Q, Tang H, Li Q, Chen L, Liu Y-G*. Genomic structural variation-mediated allelic suppression causes hybrid male sterility in rice. Nature Communications, 2017, 8(1): 1310. (IF2017=12.353)
16. Li X, Xie Y, Zhu Q, Liu Y-G*. Targeted Genome Editing in Genes and Cis-Regulatory Regions Improves Qualitative and Quantitative Traits in Crops. Molecular Plant, 2017, 10 (11):1368-1370.(IF2017=9.326)
15. Zhu Q, Yu S, Zeng D, Liu H, Wang H, Yang Z, Xie X, Shen R, Tan J, Li H, Zhao X, Zhang Q, Chen Y, Guo J, Chen L, Liu Y-G*. Development of “Purple Endosperm Rice” by engineering anthocyanin biosynthesis in the endosperm with a high-efficiency transgene stacking system. Molecular Plant, 2017, 10 (7): 918-929. (“紫晶米'',封面文章,Best of Molecular Plant 2017).(IF2017=9.326)
Highlights:
(1) Fang X, Mao Y, Chen X. Engineering purple rice for human health. Science China Life Sciences, 2018, 61(3): 365-367.
(2) 朱丽, 钱前.突破复杂性状多基因转化技术壁垒, 首创胚乳花青素高积累的水稻新种质. 植物学报, 2017,52 (5): 539-542.
14. Zhong G, Zhu Q, Li Y, Liu Y, Wang H*. Once for All: A Novel Robust System for Co-expression of Multiple Chimeric Fluorescent Fusion Proteins in Plants. Front. Plant Sci. 2017, 8:1071. doi: 10.3389/fpls.2017.01071.(IF2017=3.678)
13. Xie X, Ma X, Zhu Q, Zeng D, Li G, and Liu Y-G. CRISPR-GE: A Convenient Software Toolkit for CRISPR-Based Genome Editing. Molecular Plant, 2017, 10(9):1246-1249. (IF2017=9.326)
12. Chen W, Zhu Q, Liu Y and Zhang Q. Chromatin Remodeling and Plant Immunity. Advances in Protein Chemistry and Structural Biology. 2017, 106: 243 – 260. (IF2017=2.439)
11. Chen W, Zeng D, Shen R, Ma X, Zhang Q, Chen L, Liu Y-G*, Zhu Q*. Rapid in vitro splicing of coding sequences from genomic DNA by isothermal recombination reaction-based PCR. Biotechnology & Biotechnological Equipment, 2016, 30(5): 864-868.(IF2016=1.059)
10. Ma X, Zhu Q, Chen Y, Liu Y-G*. CRISPR/Cas9 platforms for genome editing in plants: developments and applications. Molecular Plant, 2016, 9 (7): 961-974.(IF2016=8.827)
9. Zhu Q*, Sui S, Lei X, Yang Z, Lu K, Liu G, Liu Y-G, Li M*. Ectopic Expression of the Coleus R2R3 MYB-Type Proanthocyanidin Regulator Gene SsMYB3 Alters the Flower Color in Transgenic Tobacco. PLoS One, 2015, 10 (10): e0139392.(IF2015=3.057)
8. Zhu Q*, Xie X, Lin H, Sui S, Shen R, Yang Z, Lu K, Li M, Liu Y-G*. Isolation and Functional Characterization of a Phenylalanine Ammonia-Lyase Gene (SsPAL1) from Coleus (Solenostemon scutellarioides (L.) Codd). Molecules, 2015, 20 (9): 16833-16851.(IF2015=2.465)
7. Ma X, Zhang Q, Zhu Q, Liu W, Chen Y, Qiu R, Wang B, Yang Z, Li H, Lin Y, Xie Y, Shen R, Chen S, Wang Z, Chen Y, Guo J, Chen L, Zhao X, Dong Z, and Liu Y-G*. A robust CRISPR/Cas9 system for convenient high-efficiency multiplex genome editing in monocot and dicot plants. Molecular Plant, 2015, 8(8): 1274-1284.(IF2015=7.142)
6. Ma X, Chen L, Zhu Q, Chen Y, Liu Y-G*. Rapid decoding of sequence-specific nuclease-induced heterozygous and biallelic mutations by direct sequencing of PCR products. Molecular Plant, 2015, 8(8):1285-1287. (IF2015=7.142)
5. Zhu Q*, Yang Z, Zhang Q, Chen L, Liu Y-G*. Robust multi-type plasmid modification based on isothermal in vitro recombination. Gene,2014,548(1): 39-42. (IF2014=2.138)
4. Zhu Q*, Xie X, Zhang J, Xiang G, Li Y , Wu H. In Silico Analysis of a MRP Transporter Gene Reveals Its Possible Role in Anthocyanins or Flavonoids Transport in Oryze sativa. American Journal of Plant Sciences, 2013, 4 (3):555-560.
3. Zhu QL, Guo TY, Sui SZ, Liu GD, Lei XH, Luo LL, Li MY*. Molecular cloning and characterization of a novel isoflavone reductase-like gene (FcIRL) from high flavonoids- producing callus of Fagopyrum cymosum. Acta Pharmaceutica Sinica, 2009, 44(7): 809-819.
2.Zhu QL, Li MY*, Liu GD, Li YD, Sui SZ, Guo TY. Molecular characterization and functional prediction of a novel leaf SAG encoding a CBS-domain-containing protein from Coleus blumei. Chinese Journal of Biochemistry and Molecular Biology, 2007, 23 (4):249-255 (On the cover, 封面文章).
1.Guo Y, Zhu Q, Zheng S, Li M*. Cloning of a MADS Box Gene (GhMADS3) from Cotton and Analysis of its Homeotic Role in Transgenic Tobacco. Journal of Genetics and Genomics,2007, 34(6): 527-535.
科研创新
8.一种调控作物种子直链淀粉含量和胶稠度的方法及应用(刘耀光,祝钦泷,曾栋昌),专利申请号:202010273133.1;
7.一种短小型小核RNA启动子及其构建方法和在基因组编辑中的应用(刘耀光,郭晶心,祝钦泷,郝雨,宗伍辈),专利申请号:201911338845.0;
6.一种水稻育性基因SAW1及其应用(祝钦泷,刘耀光,陈乐天,方瑞秋,王斌,陈法铭,韩靖鸾),专利申请号:20191192671.1;
5.一种多基因组装载体系统及其多基因组装方法(刘耀光,祝钦泷),专利申请号:201710384197.7;
4.一种在作物种子胚乳合成花青素的转基因育种方法(刘耀光,祝钦泷,余穗泽,曾栋昌),专利申请号:201710368951.8;
3.一种在作物种子胚乳生产虾青素的转基因育种方法(刘耀光,祝钦泷,曾栋昌,陈乐天),专利申请号:201610283794.6;
2.一种花药特异表达启动子PV4及其应用(祝钦泷,刘耀光,谭健韬),专利号:ZL201710369461.X;
1.一种水稻雄性育性可控系的构建方法及其在杂交育种的应用(刘耀光,牛百晓,王平,祝钦泷,林玉茹),专利号:ZL201210339978.1;
教学活动
2019年华南农业大学教学成果二等奖
指导学生
8. 指导2015级本科生黄银频等获得国家级大学生创新创业训练项目资助1项(201710564238);  
7.指导本科生李嘉敏等组成的SCAU-China队伍,参加2016 iGEM(国际基因工程大赛)竞赛,荣获全球总赛金奖,总决赛季军(Second Runner-Up)、“最佳新应用项目奖(Best New Application Project)、“最佳教育和公众参与奖(Best Education and    Public Engagement )” 和“植物合成生物学最佳成就奖(Best Achievement in Plant Synthetic Biology)”4个单项奖,是成绩最好的中国高校队伍;
6. 指导2014级本科生陈君宇等获2016年广东省大学生生化技能大赛三等奖;
5.指导2013级本科生崔超军等在中文核心期刊《西北植物学报》和《重庆师范大学学报-自然科学版》分别发表学术论文;
4. 指导2013级本科生崔超军等获得国家级大学生创新创业训练项目资助1项(201610564006);
3. 指导2013级本科生王建博等获得校级大学生创新创业训练项目资助1项(201610564166);
2. 指导2011级本科生陈文轩等在SCI杂志Biotechnology & Biotechnological Equipment上发表学术论文;
1. 指导2011级本科生陈文轩等获得校级大学生创新创业训练项目资助1项(SCX13111);
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