目录
更新日期:2020年6月4日
姓 名 张世海 性 别
出生年月 1989年1月 籍贯 福建建瓯市
民 族 汉族 政治面貌 群众
最后学历 博士研究生毕业 最后学位 农学博士学位
技术职称 副教授 导师类别 硕导
行政职务 Email zhangshihai@scau.edu.cn
工作单位 华南农业大学 邮政编码
通讯地址 华南农业大学新动科大楼505
单位电话
个人主页
个人简介
张世海 副教授,动物营养学博士,硕士生导师。North Carolina State University(NCSU)联合培养博士。2019-2020年在美国德州大学西南医学中心任客座副教授。研究方向包括:1. 母仔猪营养、2. 泌乳营养调控。先后主持国家自然基金青年基金项目1项,十三五国家重点研发计划重点专项子课题1项,广东省自然科学基金1项,华南农业大学青年科技人才专项培育基金1项。同时,参与国家自然基金、十三五国家重点研发计划等多项国家和省部级项目。以第一或通讯作者在Journal of Agricultural and Food chemistry, Food & Function,Nutrition Research Reviews等杂志发表SCI论文30余篇。是 Journal of Agricultural and Food chemistry,Journal of Animal Science,Food and Functions,Frontiers in Immunology,Frontiers in Microbiology,Animals, Scientific Reports,Livestock Science,Animal Nutrition,Genomics,Food Bioscience等杂志审稿人。主讲《动物营养学》、《饲料学》等专业课课程。Email: zhangshihai@scau.edu.cn
工作经历
2016-2019:华南农业大学,动物科学,首聘副教授
2020-       :华南农业大学,动物科学,副教授
2019-2020: 美国德州大学西南医学中心,分子生物学,客座副教授
教育经历
2014-2015:North Carolina State University,动物科学,联合培养博士
2011-2016:中国农业大学,动物营养与饲料科学,博士
2007-2011:中国农业大学,动物科学,学士
获奖、荣誉称号
2018年 华南农业大学 “青年教师教学优秀奖” 一等奖
2018年 华南农业大学 动物科学学院 “教学十佳”
2019年 华南农业大学 动物科学学院“青年教师成长奖”
研究领域
主要研究方向包括母仔猪营养、氨基酸营养、仔猪肠道健康与功能等
科研项目
主要主持项目
1 肠道氨基酸感知受体介导支链氨基酸调控仔猪采食量的机制研(31802067) ,国家科学自然基金委,25W, 2019.1-2021.12 (主持人)
2 肠道和大脑氨基酸感知受体介导支链氨基酸调控仔猪采食量的机制研究 (2018A030310201) 广东省自然科学基金,10 W,2018.5.1-2021.4.30 (主持人)
3 胃肠道氨基酸感知受体影响仔猪采食量的作用机制,华南农业大学青年科技人才培育专项基金,20W, 2017.1-2018.12 (主持人)
主要参与项目
1 长链脂肪酸调节母猪乳脂合成的分子机制(31872364),国家科学自然基金委,59W,2019.1-2022.12 第2(管武太主持)
2 不同种类和加工工艺的油脂对肠道稳态和肠道微生物菌群定植的影响(2017YFD0500501),国家重点研发计划项目,31W,2017.9-2020.12,第2(管武太主持)
发表论文
1. Heng, J., Tian, M., Zhang, W., Chen, F., Guan, W., & Zhang, S. (2019). Maternal heat stress regulates the early fat deposition partly through modification of m 6 A RNA methylation in neonatal piglets. Cell Stress and Chaperones, 24(3), 635-645.(通讯作者)
2. Tian, M., Heng, J., Song, H., Shi, K., Lin, X., Chen, F., ... & Zhang, S. (2019). Dietary Branched-chain Amino Acids Regulate Food Intake Partly through Intestinal and Hypothalamic Amino Acid Receptors in Piglets. Journal of agricultural and food chemistry. (通讯作者)
3. Tian, M., Heng, J., Song, H., Zhang, Y., Chen, F., Guan, W., & Zhang, S. (2019). Branched chain amino acids stimulate gut satiety hormone cholecystokinin secretion through activation of the umami taste receptor T1R1/T1R3 using an in vitro porcine jejunum model. Food & function. (通讯作者)
4. Li, L., Zhang, S., Wu, W., Guan, W., Deng, Z., & Qiao, H. (2019). Enhancing thermostability of Yarrowia lipolytica lipase 2 through engineering multiple disulfide bonds and mitigating reduced lipase production associated with disulfide bonds. Enzyme and microbial technology, 126, 41-49. (并列一作)
5. Zhang, S., Heng, J., Song, H., Zhang, Y., Lin, X., Tian, M., ... & Guan, W. (2019). Role of maternal dietary protein and amino acids on fetal programming, early neonatal development, and lactation in swine. Animals, 9(1), 19.
6. Zhang S, Chen F, Zhang Y, Lv Y, Heng J, Min T, Guan W. (2018). Recent progress of porcine milk components and mammary gland function. Journal of animal science and biotechnology, 9(1): 77
7. Zhang, S., Tian, M., Song, H., Shi, K., Wang, Y., & Guan, W. (2018). Effects of L-carnitine on reproductive performance, milk composition, placental development and IGF concentrations in blood plasma and placental chorions in sows. Archives of animal nutrition, 1-14.
8. Zhang, S., Zhang, X., Qiao, H., Chen, J., Fang, C., Deng, Z., & Guan, W. (2018). Effect of timing of post-weaning supplementation of soybean oil and exogenous lipase on growth performance, blood biochemical profiles, intestinal morphology and caecal microbial composition in weaning pigs. Italian Journal of Animal Science, 1-9.
9. Zhang, S., Song, J., Deng, Z., Cheng, L., Tian, M., & Guan, W. (2017). Effects of combined α-galactosidase and xylanase supplementation on nutrient digestibility and growth performance in growing pigs. Archives of animal nutrition, 71(6), 441-454.
10. Zhang, S. H., S. Y. Qiao, M. Ren, X. F. Zeng, X. Ma, Z. L. Wu, P. A. Thacker, and G. Y. Wu. 2013. Supplementation with branched-chain amino acids to a low-protein diet regulates intestinal expression of amino acid and peptide transporters in weanling pigs. Amino Acids, 45:1191-1205.
11. Zhang, S. H., M. Ren, X. F. Zeng, P. L. He, X. Ma, and S. Y. Qiao. 2014. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways. Amino Acids, 46: 2633-2642.
12. Zhang, S. H., L. C. Chu, X. B. Mao, and S. Y. Qiao. 2015. Effects of dietary leucine supplementation in low crude protein diets on performance, nitrogen balance, whole-body protein turnover, carcass characteristics and meat quality of finishing pigs. Anim. Sci. J., 87:911-920.
13. Zhang, S. H., Q. Yang, M. Ren, S. Y. Qiao, P. L. He and X. F. Zeng. 2016. Effects of isoleucine on glucose uptake through the enhancement of muscular membrane concentrations of GLUT1 and GLUT4 and intestinal membrane concentrations of SGLT-1 and GLUT2. Br. J. Nutr. 116:593-602.
14. Zhang, S. H., Zeng, X. F., Ren, M., Mao, X. B., and Qiao, S. Y. 2017. Novel metabolic and physiological functions of branched chain amino acids: a review. J Anim. Sci. Biotechno., 8: 10.
15. Zhang, Y., Zhang, S., Guan, W., Chen, F., Cheng, L., Lv, Y., & Chen, J. (2018). GLUT1 and lactose synthetase are critical genes for lactose synthesis in lactating sows. Nutrition & Metabolism, 15(1), 40. (并列一作)
16. Yang F, Zhang S H, Kim S W, et al. Fat encapsulation enhances dietary nutrients utilization and growth performance of nursery pigs[J]. Journal of animal science, 2018: sky217. (并列一作)
17. Ma, W. F., S. H. Zhang, X. F. Zeng, X. T. Liu, C. Y. Xie, G. J. Zhang, and S. Y. Qiao. 2015. Appropriate standardized ileal digestible tryptophan to lysine ratio improve pig performance and regulate hormones and muscular amino acid transporter in late finishing gilts fed low protein diets. J. Anim. Sci., 93:1052-1060. (并列一作)
18. Ren, M., S. H. Zhang, X. T. Liu, S. H. Li, X. B. Mao, X. F. Zeng, and S. Y. Qiao. 2016. Different LPS, branched-chain amino acids modulate porcine intestinal endogenous β-defensin expression through Sirt1/ERK/90RSK pathway. J. Agric. Food Chem., 64: 3371-3379. (并列一作)
19. Chen, F., Zhang, S., Deng, Z., Zhou, Q., Cheng, L., Kim, S. W., ... & Guan, W. (2018). Regulation of amino acid transporters in the mammary gland from late pregnancy to peak lactation in the sow. Journal of animal science and biotechnology, 9(1), 35.
20. Jia, H., He, T., Yu, H., Zeng, X., Zhang, S., Ma, W., ... & Ma, X. (2019). Effects of L-lysine· H 2 SO 4 product on the intestinal morphology and liver pathology using broiler model. Journal of animal science and biotechnology, 10(1), 10.
21. Chen, J., Tian, M., Guan, W., Wen, T., Yang, F., Chen, F., ... & Song, H. (2019). Increasing selenium supplementation to a moderately-reduced energy and protein diet improves antioxidant status and meat quality without affecting growth performance in finishing pigs. Journal of Trace Elements in Medicine and Biology, 56, 38-45.
22. Chen, J., Zhang, F., Guan, W., Song, H., Tian, M., Cheng, L., ... & Yang, F. (2019). Increasing selenium supply for heat-stressed or actively cooled sows improves piglet preweaning survival, colostrum and milk composition, as well as maternal selenium, antioxidant status and immunoglobulin transfer. Journal of Trace Elements in Medicine and Biology, 52, 89-99.
23. Ren, M., Cai, S., Zhou, T., Zhang, S., Li, S., Jin, E., ... & Qiao, S. (2019). Isoleucine attenuates infection induced by E. coli challenge through the modulation of intestinal endogenous antimicrobial peptide expression and the inhibition of the increase in plasma endotoxin and IL-6 in weaned pigs. Food & function.
24. Xie, C. Y., S. H. Zhang, G. J. Zhang, F. R. Zhang, L. C. Chu, and S. Y. Qiao. 2013. Estimation of the optimal ratio of standardized ileal digestible threonine to lysine for finishing barrows fed low crude protein diets. Asian-Aust. J. Anim. Sci., 26:1172-1180.
25. Ren, M., S. H. Zhang, X. F. Zeng, H. Liu, and S. Y. Qiao. 2015 Branched-chain amino acids are beneficial to maintain growth performance and intestinal immune-related function in weaned piglets fed protein restricted diet. Asian-Aust. J. Anim. Sci., 28:1742-1750.
26. Yu, C. Y., S. H. Zhang, Q. Yang, Q. Peng, J. L. Zhu, X. F. Zeng, and S. Y. Qiao. 2016. Effect of high fibre diets formulated with different fibrous ingredients on performance, nutrient digestibility and faecal microbiota of piglets. Arch. Anim. Nutr., 4:263-277.
27. Liu, H., J. Zhang, S. H. Zhang, F. J. Yang, P. A. Thacker, G. R. Zhang, S. Y.Qiao, and X. Ma. 2014. Oral administration of Lactobacillus fermentum I5007 favors intestinal development and alters the intestinal microbiota in formula-fed piglets. J. Agric. Food. Chem., 62:860-866.
28. Hou, C. H., H. Liu, J. Zhang, S. H. Zhang, F. J. Yang, X. F. Zeng, P. A. Thacker, G. R. Zhang, and S. Y. Qiao. 2015. Intestinal microbiota succession and immunomodulatory consequences after introduction of Lactobacillus reuteri I5007 in neonatal piglets. PLoS One, 10:e0119505.
29. Xie, C. Y., G. J. Zhang, F. R. Zhang, S. H. Zhang, X. F. Zeng, P. A., Thacker, and S. Y. Qiao. 2014. Estimation of the optimal ratio of standardized ileal digestible tryptophan to lysine for finishing barrows fed low protein diets supplemented with crystalline amino acids. Czech J. Anim. Sci., 59: 26-34.
30. Zeng, X. F., Z. M. Huang, F. R. Zhang, X. B. Mao, S. H. Zhang, S. Y. Qiao. 2015. Oral administration of N-Carbamylglutamate might improve growth performance and intestinal function of suckling piglets. Livest. Sci., 181:242-248.
31. 田敏,恒景会,张文飞,陈芳,邓跃林,管武太,张世海(*). 饲粮营养素调控母猪泌乳性能的研究进展. 中国畜牧杂志 2018;(10):9-14.
32. 张世海,王雅春,俞英,潘敦菲,郭黎宁,和思淼,王鹏,齐思锦,牛牧田.2009.北京市家庭奶制品消费调查.中国乳业,11:36-37.
33. 张世海,谢春元,谯仕彦.2012.低蛋白日粮添加功能性氨基酸对断奶仔猪生长性能影响的研究.见:印遇龙,编. 中国畜牧兽医学会动物营养学分会第十一次全国动物营养学术研讨会论文集.长沙:pp 374.
34. 谢春元,张世海,谯仕彦.2012.低蛋白日粮饲喂条件下肥育猪标准回肠可消化苏氨酸与赖氨酸最佳比值的测定.见:印遇龙,编.中国畜牧兽医学会动物营养学分会第十一次全国动物营养学术研讨会论文集.长沙:pp 373.
35. 何贝贝,李天天,朱玉华,周天骄,戴兆来,张世海,薛欣合,臧建军,王军军.2014.不同生长性能猪肠道菌群差异分析.动物营养学报,26(8):2327-2334.
科研创新
管武太,邓子潇,李力浪,吴炜坤,张世海. 一种耐热突变脂肪酶及制备方法与应用. 申请号:201711220144.8
管武太,李力浪,吴炜坤,邓子潇,张世海. 一种能提高耐热脂肪酶产量的重组工程菌及其构建方法和应用. 申请号:201711220171.5
管武太, 张世海,陈芳,桂干北,乔汉祯,谌俊. 一种改善母猪繁殖性能和抗氧化能力的组合物及其应用. 申请号: 201710361392.8
教学活动
本科生课程:《动物营养学》、《饲料学》、《饲料学综合实习》
研究生课程:《猪营养研究专题》
指导学生情况
指导学术型研究生1名,专业硕1名,合作指导研究生10名
我的团队
管武太教授 母仔猪营养团队。 本团队包括教授1名,副教授3名。